نبذة عن نائب الرئيس

أ.د. عادل محمد أبو زنادة


العنوان الدائم:
صندوق بريد رقم 80216 جدة – 21589 المملكة العربية السعودية

الهاتف:
64000000(012) 966+ تحويلة: 52050 - 62531

البريد الإلكتروني:
aabuzenadah@kau.edu.sa - adel_abuzenadah@hotmail.com

  • يناير 2023 – حاليا

    نائب رئيس جامعة الملك عبدالعزيز للشؤون التعليمية.

  • يونيو 2018 – ديسمبر 2022

    المشرف العام على الإدارة العامة للخدمات التعليمية بجامعة الملك عبدالعزيز.

  • ديسمبر 2017 – ديسمبر 2022

    مدير مركز الملك فهد للبحوث الطبية بجامعة الملك عبدالعزيز.

  • فبراير 2017 – ديسمبر 2022

    مدير مبادرة توفير الخدمات الطبية والمخبرية بجامعة الملك عبدالعزيز (إحدى مبادرات التحول الوطني).

  • يونيو 2013 – مارس 2017

    عميد كلية العلوم الطبية التطبيقية بجامعة الملك عبدالعزيز.

  • يناير 2015 – مارس 2017

    عميد كلية التأهيل الطبي المكلف بجامعة الملك عبدالعزيز.

  • يونيو 2013 – مايو 2017

    وكيل كلية العلوم الطبية التطبيقية بجامعة الملك عبدالعزيز.

  • يونيو 2013 – حتى يونيو 2014

    عميد كلية التمريض بجامعة الملك عبدالعزيز.

  • يناير 2013 – ابريل 2017

    مدير مركز الابتكار في الطب الشخصي بجامعة الملك عبدالعزيز.

  • مارس 2006 – ابريل 2017

    نائب مدير مركز التميز البحثي في علوم الجينوم الطبي بجامعة الملك عبدالعزيز.

  • مارس 2011 – يونيو 2013

    نائب مدير مركز الملك فهد للبحوث الطبية بجامعة الملك عبدالعزيز.

  • مارس 2005 – فبراير 2011

    نائب عميد كلية العلوم الطبية التطبيقية بجامعة الملك عبدالعزيز.

  • يناير 2004 – حتى مارس 2005

    رئيس قسم المختبرات الطبية بكلية العلوم الطبية التطبيقية.

  • ابريل 2001

    عضو في الفريق المسؤول عن إنشاء وحدة الجينوم الطبي في مركز الملك فهد للبحوث والطبية ومدير التشخيص الطبي في هذه الوحدة حتى الآن وكانت الوحدة نواة إنشاء مركز التميز البحثي في علوم الجينوم الطبي لاحقاً في عام 2006م.

  • مارس 2014 - حتى الان

    أستاذ أمراض الدم بقسم تقنية المختبرات الطبية كلية العلوم الطبية التطبيقية بجامعة الملك عبدالعزيز.

  • فبراير 2010 - حتى مارس 2014

    أستاذ مشارك أمراض الدم بقسم تقنية المختبرات الطبية كلية العلوم الطبية التطبيقية بجامعة الملك عبدالعزيز.

  • مايو 1999 – فبراير 2010

    أستاذ مساعد أمراض الدم بقسم تقنية المختبرات الطبية كلية العلوم الطبية التطبيقية بجامعة الملك عبدالعزيز.

  • مايو 1992 – مايو 1999

    معيد أكاديمي في تخصص أمراض الدم الوراثية بقسم المختبرات الطبية كلية العلوم الطبية التطبيقية بجامعة الملك عبدالعزيز.

  • BSc Medical Technology

    1987-1991
    Faculty of Medicine & Allied Health Sciences
    King Abdulaziz University

  • MSc pathological Sciences

    1993-1994
    Sheffield Hallam University and Sheffield University
    Specialty subject: Hematology

  • PhD in molecular hematology (supspecialized in Coaugulation)

    1994-1998
    Sheffield University
    Division of Molecular and Genetic Medicine

  • PhD Research

    Characterization of the Molecular Basis of von Willebrand’s Disease.

  • Over the years and since I came back from my scholarship from UK in December 1998, I was continuously involved in administration starting as head of departments and moving through different positions as mentioned above and in recent years as dean for more than one college.
  • I was involved heavily in curriculum developments and I am now the head of the curriculum committee at both faculty of applied medical sciences and faculty of medical rehabilitation. I was directly responsible of establishing and reviewing the curriculum of several BSc programs in both colleges including:
    • Medical laboratory technology
    • Clinical nutrition
    • Nursing
    • Diagnostic imaging
    • Physiotherapy
    • Occupational therapy
    • Speech pathology & Audiology
    • Respiratory therapy
    • Prosthetics
  • I was member of several committees in the university the most important of all are:
    • University board
    • University dean’s committee
    • King Fahad medical research center steering committee
    • Center of innovation in personalized medicine steering committee
    • Executive university committee for student scientific conferences and activities.
    • Health colleges Dean’s steering committee.
    • Head of faculty board committee.
  • I was the head of the committees responsible about accreditation of all programs in the faculty of applied medical sciences. We have successfully accredited the medical laboratory program by the institute of biomedical sciences (IBMS) from UK. We have recently succeeded in getting the international accreditation for clinical nutrition, physiotherapy and diagnostic radiology programs. These were accredited by the Accreditation Agency in Health and Social Sciences (AHPGS) from Germany.
  • Over the years in the university, I have attended conferences and workshops and training programs in my specialty as molecular hematologist or as administrator in building leaders and leadership. These activities were inside the university and outside the university both locally inside Saudi Arabia and in different international locations.

  • Member of the team responsible of developing the genomic medicine unit (GMU) lab at king Fahad Medical research center. GMU is now serving patients of king Abdulaziz university hospital and other near by hospitals. Several specialized laboratory investigations are performed including chromosomal analysis and several molecular testing for various diseases such as qualitative and quantitative analysis of gene fusions in leukemia and detection of mutations causing thrombophilia and other diseases. We also provide diagnostic of common genetic disorders, cancer diagnostics and follow up of effect of treatment on patient’s genes. I am responsible of signing off reports for patients for the diagnostic services performed at this unit and at center of innovation in personalized medicine.
  • Member of the team responsible of establishing Center of Excellence in Genomic Medicine Research. This center is supported by ministry of higher education and is considered one of a kind in kingdom of Saudi Arabia.
  • During PhD research, I have gained experiences in several molecular techniques including different forms of PCR, gel electrophoresis, restriction enzyme analysis, primer design, several mutation detection methods, direct manual and automated DNA sequencing, family studies and cell transfection analysis.
  • Several other experiences have been gained during research and diagnostic work in molecular and hematology lab such as real time PCR and some of its applications and basic hematology lab analysis such as using cell counters, coagulation tests, and others.
  • Recently, I have been involved in setting up research and diagnostic tests using micro array technology and I have received special training on using infinity analyzer produced by Autogenomic. This is beside new addition of equipment to our lab such as affymetrix system and Agelant system as well ad next generation sequencers.
  • I am now the director of the diagnostic medical laboratory initiative funded by the government as part of the reform of 2020 and the vision of 2030 of the Kingdom of Saudi Arabia.

Please contact me for my references as they are president and vice-president of the university and I cannot post their contacts in public. I can provide you with all required information upon your request.

1 Rasool M, Karim S, Naseer MI, Pushparaj PN, Abuzenadah A, Al-Qahtani MH. Gene mapping and molecular analysis of hereditarynon-polyposis colorectal cancer (Lynch Syndrome) using systems biological approaches. 2019 Apr 15;15(4):269-276.
2 brahim SM, Karim S, Abusamra H, Pushparaj PN, Khan JA, Abuzenadah AM, Gari MA, Bakhashab S, Ahmed F, Al-Qahtani MH. Genomic amplification of chromosome 7 in the Doxorubicin resistant K562 cell line. 2018 Dec 29;14(9):587-593.
3 Ibrahim SM, Bakhashab S, Ilyas AM, Pushparaj PN, Karim S, Khan JA, Abuzenadah AM, Chaudhary AG, Al-Qahtani MH, Ahmed F. WYE-354 restores Adriamycin sensitivity in multidrug-resistant acute myeloid leukemia cell lines. 2019 Jun;41(6):3179-3188
4 Beg MA, Nieschlag E, Abdel-Meguid TA, Alam Q, Abdelsalam A, Haque A, Mosli HA, Bajouh OS, Abuzenadah AM, Al-Qahtani M.Genetic investigations on causes of male infertility in Western Saudi Arabia. 2019 Jul;51(6):e13272.
5 Abuzenadah A, Al-Saedi S, Karim S, Al-Qahtani M. Malignant Transformation and Spine Metastasis of an Intracranial Grade I Meningioma: In Situ Immunofluorescence Analysis of Cancer Stem Cells Case Report and Literature Review. 2018 Dec;120:274-289.
6 Baeesa SS, Hussein D, Altalhy A, Bakhaidar MG, Alghamdi FA, Bangash M, Abuzenadah A. Malignant Transformation and Spine Metastasis of an Intracranial Grade I Meningioma: In Situ Immunofluorescence Analysis of Cancer Stem Cells Case Report and Literature Review. 2018 Dec;120:274-289.
7 Khatoon A, Khan F, Ahmad N, Shaikh S, Rizvi SMD, Shakil S, Al-Qahtani MH, Abuzenadah AM, Tabrez S, Ahmed ABF, Alafnan A, Islam H, Iqbal D, Dutta R. Silver nanoparticles from leaf extract of Mentha piperita: Eco-friendly synthesis and effect on acetylcholinesterase activity. 2018 Sep 15;209:430-434.
8 Aljuhani SH, Bamaroof SA, Alghamdi TH, Almogbel AA, Alkhammash AS, Alkhammash BS, Bahusayn AA, Bangash MH, Baeesa SS, Chaudhary AG, Abuzenadah AM, Mirza AA, Saka MY, Hussein DM. Public awareness of central nervous system tumors in the Kingdom of Saudi Arabia. 2018 Jul;23(3):227-237.
9 Alamir H, Alomari M, Salwati AAA, Saka M, Bangash M, Baeesa S, Alghamdi F, Carracedo A, Schulten HJ, Chaudhary A, Abuzenadah A, Hussein D. In situ characterization of stem cells-like biomarkers in meningiomas. 2018 May 25;18:77.
10 Khan F, Aldhahri M, Hussain MA, Gauthaman K, Memic A, Abuzenadah A, Kumosani T, Barbour E, Alothmany NS, Aldhaheri RW. Encapsulation of 5-Flurouracil into PLGA Nanofibers and Enhanced Anticancer Effect in Combination with Ajwa-Dates-Extract (Phoenix dactylifera L.). 2018 Mar 1;14(3):553-563.
11 Buhmeida A, Assidi M, Al-Maghrabi J, Dallol A, Sibiany A, Al-Ahwal M, Chaudhary A, Abuzenadah A, Al-Qahtani M. Membranous or Cytoplasmic HER2 Expression in Colorectal Carcinoma: Evaluation of Prognostic Value Using Both IHC & BDISH. 2018 Feb 7;36(2):129-140.
12 Bahamat AA, Assidi M, Lary SA, Almughamsi MM, Peer Zada AA, Chaudhary A, Abuzenadah A, Abu-Elmagd M, Al-Qahtani M. Use of Array Comparative Genomic Hybridization for the Diagnosis of DiGeorge Syndrome in Saudi Arabian Population. 2018;154(1):20-29.
13 Shakil S, Baig MH, Tabrez S, Rizvi SMD, Zaidi SK, Ashraf GM, Ansari SA, Khan AAP, Al-Qahtani MH, Abuzenadah AM, Chaudhary AG. Molecular and enzoinformatics perspectives of targeting Polo-like kinase 1 in cancer therapy. 2019 Jun;56:47-55.
14 Khan F, Khan TJ, Kalamegam G, Pushparaj PN, Chaudhary A, Abuzenadah A, Kumosani T, Barbour E, Al-Qahtani M. Anti-cancer effects of Ajwa dates (Phoenix dactylifera L.) in diethylnitrosamine induced hepatocellular carcinoma in Wistar rats. 2017 Aug 22;17(1):418.
15 Alsofyani AA, Alsiary RA, Samkari A, Alhaj-Hussain BT, Khan JA, Al-Maghrabi J, Elaimi A, Al-Qahtani MH, Abuzenadah AM, Dallol A. Prognostic potential of KLOTHO and SFRP1 promoter methylation in head and neck squamous cell carcinoma. 2017 Nov;58(4):459-465.
16 Khan I, Baeesa S, Bangash M, Schulten HJ, Alghamdi F, Qashqari H, Madkhali N, Carracedo A, Saka M, Jamal A, Al-Maghrabi J, AlQahtani M, Al-Karim S, Damanhouri G, Saini K, Chaudhary A, Abuzenadah A, Hussein D. Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines. 2017 Jul 21;17:72.
17 Merdad L, Aldakhil L, Gadi R, Assidi M, Saddick SY, Abuzenadah A, Vaught J, Buhmeida A, Al-Qahtani MH. Assessment of knowledge about biobanking among healthcare students and their willingness to donate biospecimens. 2017 May 2;18(1):32.
18 Karim S, Jamal HS, Rouzi A, Ardawi MSM, Schulten HJ, Mirza Z, Alansari NA, Al-Quaiti MM, Abusamra H, Naseer MI, Turki R, Chaudhary AG, Gari M, Abuzenadah AM, Al-Qhatani MH.Genomic answers for recurrent spontaneous abortion in Saudi Arabia: An array comparative genomic hybridization approach. 2017 Jun;17(2):133-143.
19 Naseer MI, Rasool M, Sogaty S, Chaudhary RA, Mansour HM, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH. A novel WDR62 mutation causes primary microcephaly in a large consanguineous Saudi family. 2017 Mar-Apr;37(2):148-153.
20 Shaikh S, Rizvi SMD, Shakil S, Hussain T, Alshammari TM, Ahmad W, Tabrez S, Al-Qahtani MH, Abuzenadah AM. Synthesis and Characterization of Cefotaxime Conjugated Gold Nanoparticles and Their Use to Target Drug-Resistant CTX-M-Producing Bacterial Pathogens. 2017 Sep;118(9):2802-2808.
21 Bibi F, Yasir M, Alvi SA, Azhar EI, Al-Ghamdi AA, Abuzenadah AM, Raoult D, Angelakis E. Halomonas saudii' sp. nov., a new bacterial species isolated from marine plant Halocnemum strobilaceum. 2016 Nov 15;15:42-43.
22 Gari M, Alsehli H, Gari A, Abbas M, Alkaff M, Abuzinadah M, Al-Sayes F, Gari M, Dallol A, Abuzenadah AM, Gauthaman K. Derivation and differentiation of bone marrow mesenchymal stem cells from osteoarthritis patients. 2016 Dec 17;13(6):732-739.
23 Naseer MI, Rasool M, Jan MM, Chaudhary AG, Pushparaj PN, Abuzenadah AM, Al-Qahtani MH. A novel mutation in PGAP2 gene causes developmental delay, intellectual disability, epilepsy and microcephaly in consanguineous Saudi family. 2016 Dec 15;371:121-125.
24 Turki RF, Assidi M, Banni HA, Zahed HA, Karim S, Schulten HJ, Abu-Elmagd M, Rouzi AA, Bajouh O, Jamal HS, Al-Qahtani MH, Abuzenadah AM. Associations of recurrent miscarriages with chromosomal abnormalities, thrombophilia allelic polymorphisms and/or consanguinity in Saudi Arabia. 2016 Oct 10;17(Suppl 1):69.
25 Bibi F, Naseer MI, Alvi SA, Yasir M, Jiman-Fatani AA, Sawan A, Abuzenadah AM, Al-Qahtani MH, Azhar EI. microRNA analysis of gastric cancer patients from Saudi Arabian population. 2016 Oct 17;17.
26 Sheikh IA, Ahmad E, Jamal MS, Rehan M, Assidi M, Tayubi IA, AlBasri SF, Bajouh OS, Turki RF, Abuzenadah AM, Damanhouri GA, Beg MA, Al-Qahtani M. Spontaneous preterm birth and single nucleotide gene polymorphisms: a recent update. 2016 Oct 17;17(Suppl 9):759. Review.
27 Gari MA, AlKaff M, Alsehli HS, Dallol A, Gari A, Abu-Elmagd M, Kadam R, Abuzinadah MF, Gari M, Abuzenadah AM, Gauthaman K, Alkhatabi H, Abbas MM. Identification of novel genetic variations affecting osteoarthritis patients. 2016 Oct 10;17(Suppl 1):68.
28 Abu-Elmagd M, Assidi M, Dallol A, Buhmeida A, Pushparaj PN, Kalamegam G, Al-Hamzi E, Shay JW, Scherer SW, Agarwal A, Budowle B, Gari M, Chaudhary A, Abuzenadah A, Al-Qahtani M. The Third International Genomic Medicine Conference (3rd IGMC, 2015): overall activities and outcome highlights. 2016 Oct 17;17(Suppl 9):747.
29 Karim S, Al-Maghrabi JA, Farsi HM, Al-Sayyad AJ, Schulten HJ, Buhmeida A, Mirza Z, Al-Boogmi AA, Ashgan FT, Shabaad MM, NourEldin HF, Al-Ghamdi KB, Abuzenadah A, Chaudhary AG, Al-Qahtani MH. Cyclin D1 as a therapeutic target of renal cell carcinoma- a combined transcriptomics, tissue microarray and molecular docking study from the Kingdom of Saudi Arabia. 2016 Sep 30;16(Suppl 2):741.
30 Dallol A, Daghistani K, Elaimi A, Al-Wazani WA, Bamanie A, Safiah M, Sagaty S, Taha L, Zahed R, Bajouh O, Chaudhary AG, Gari MA, Turki R, Al-Qahtani MH, Abuzenadah AM. Utilization of amplicon-based targeted sequencing panel for the massively parallel sequencing of sporadic hearing impairment patients from Saudi Arabia. 2016 Oct 10;17(Suppl 1):67.
31 Sheikh IA, Yasir M, Abu-Elmagd M, Dar TA, Abuzenadah AM, Damanhouri GA, Al-Qahtani M, Beg MA. Human sex hormone-binding globulin as a potential target of alternate plasticizers: an in silico study. 2016 Sep 30;16(Suppl 1):15.
32 Shaikh S, Rizvi SM, Suhail T, Shakil S, Abuzenadah AM, Anis R, Naaz D, Dallol A, Haneef M, Ahmad A, Choudhary L. Prediction of Anti-Diabetic Drugs as Dual Inhibitors Against Acetylcholinesterase and Beta-Secretase: A Neuroinformatics Study. 2016;15(10):1216-1221.
33 Al-Attas A, Assidi M, Al-Maghrabi J, Dallol A, Schulten HJ, Abu-Elmagd M, Chaudhary A, Abuzenadah A, Budowle B, Buhmeida A, Al-Qahtani M. Enhancement of Pathologist's Routine Practice: Reuse of DNA Extracted from Immunostained Formalin-fixed Paraffin-embedded (FFPE) Slides in Downstream Molecular Analysis of Cancer. 2016 09-10;13(5):399-406.
34 Nedjadi T, Al-Maghrabi J, Assidi M, Dallol A, Al-Kattabi H, Chaudhary A, Al-Sayyad A, Al-Ammari A, Abuzenadah A, Buhmeida A, Al-Qahtani M. Prognostic value of HER2 status in bladder transitional cell carcinoma revealed by both IHC and BDISH techniques. 2016 Aug 19;16:653. doi: 10.1186/s12885-016-2703-5.
35 Hussein IR, Magbooli A, Huwait E, Chaudhary A, Bader R, Gari M, Ashgan F, Alquaiti M, Abuzenadah A, AlQahtani M. Genome wide array-CGH and qPCR analysis for the identification of genome defects in Williams' syndrome patients in Saudi Arabia. 2016 Aug 12;9:65.
36 Khan F, Ahmed F, Pushparaj PN, Abuzenadah A, Kumosani T, Barbour E, AlQahtani M, Gauthaman K. Ajwa Date (Phoenix dactylifera L.) Extract Inhibits Human Breast Adenocarcinoma (MCF7) Cells In Vitro by Inducing Apoptosis and Cell Cycle Arrest. 2016 Jul 21;11(7):e0158963.
37 Kalamegam G, Abbas M, Gari M, Alsehli H, Kadam R, Alkaff M, Chaudhary A, Al-Qahtani M, Abuzenadah A, Kafienah W, Mobasheri A. Pelleted Bone Marrow Derived Mesenchymal Stem Cells Are Better Protected from the Deleterious Effects of Arthroscopic Heat Shock. 2016 May 24;7:180.
38 Karim S, Merdad A, Schulten HJ, Jayapal M, Dallol A, Buhmeida A, Al-Thubaity F, Mirza Z, Gari MA, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH. Low expression of leptin and its association with breast cancer: A transcriptomic study. 2016 Jul;36(1):43-8.
39 Dallol A, Buhmeida A, Al-Ahwal MS, Al-Maghrabi J, Bajouh O, Al-Khayyat S, Alam R, Abusanad A, Turki R, Elaimi A, Alhadrami HA, Abuzenadah M, Banni H, Al-Qahtani MH, Abuzenadah AM. Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples. 2016 May 4;14(1):118.
40 Sheikh IA, Turki RF, Abuzenadah AM, Damanhouri GA, Beg MA. Endocrine Disruption: Computational Perspectives on Human Sex Hormone-Binding Globulin and Phthalate Plasticizers. 2016 Mar 10;11(3):e0151444.
41 Karim S, Mirza Z, Chaudhary AG, Abuzenadah AM, Gari M, Al-Qahtani MH. Assessment of Radiation Induced Therapeutic Effect and Cytotoxicity in Cancer Patients Based on Transcriptomic Profiling. 2016 Feb 19;17(2):250.
42 Alwazani WA, Zahid R, Elaimi A, Bajouh O, Hindawi S, Arab B, Damanhouri G, Saka MY, Turki R, Khan JA, Dallol A, Abuzenadah AM. Detection of β-Thalassemia Mutations Using TaqMan Single Nucleotide Polymorphism Genotyping Assays. 2016 Mar;20(3):154-7.
43 Rizvi SM, Shaikh S, Naaz D, Shakil S, Ahmad A, Haneef M, Abuzenadah AM. Kinetics and Molecular Docking Study of an Anti-diabetic Drug Glimepiride as Acetylcholinesterase Inhibitor: Implication for Alzheimer's Disease-Diabetes Dual Therapy. 2016 Jun;41(6):1475-82.
44 Bakhashab S, Ahmed FW, Schulten HJ, Bashir A, Karim S, Al-Malki AL, Gari MA, Abuzenadah AM, Chaudhary AG, Alqahtani MH, Lary S, Ahmed F, Weaver JU. Metformin improves the angiogenic potential of human CD34⁺ cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction. 2016 Feb 9;15:27.
45 Salem N, Kamal I, Al-Maghrabi J, Abuzenadah A, Peer-Zada AA, Qari Y, Al-Ahwal M, Al-Qahtani M, Buhmeida A. High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma. 2016 Feb;12(3):323-31.
46 Al-Maghrabi J, Emam E, Gomaa W, Al-Qaydy D, Al-Maghrabi B, Buhmeida A, Abuzenadah A, Al-Qahtani M, Al-Ahwal M. Overexpression of PAK-1 is an independent predictor of disease recurrence in colorectal carcinoma. 2015 Dec 1;8(12):15895-902.
47 Shaikh S, Shakil S, Abuzenadah AM, Rizvi SM, Roberts PM, Mushtaq G, Kamal MA. Nanobiotechnological Approaches Against Multidrug Resistant Bacterial Pathogens: An Update. Curr Drug Metab. 2015;16(5):362-70
48 Rehan M, Ahmad E, Sheikh IA, Abuzenadah AM, Damanhouri GA, Bajouh OS, AlBasri SF, Assiri MM, Beg MA. Androgen and Progesterone Receptors Are Targets for Bisphenol A (BPA), 4-Methyl-2,4-bis-(P-Hydroxyphenyl)Pent-1-Ene--A Potent Metabolite of BPA, and 4-Tert-Octylphenol: A Computational Insight. PLoS One. 2015 Sep 17;10(9):e0138438. doi: 10.1371/journal.pone.0138438
49 Agarwal A, Ayaz A, Samanta L, Sharma R, Assidi M, Abuzenadah AM, Sabanegh E. Comparative proteomic network signatures in seminal plasma of infertile men as a function of reactive oxygen species. Clin Proteomics. 2015 Aug 28;12(1):23. doi: 10.1186/s12014-015-9094-5.
50 Shaikh S, Aaqil H, Rizvi SM, Shakil S, Abuzenadah AM, Gupta P, Saxena S,Tiwari RK, Kumar A. Comparative Inhibition Study of Compounds Identified in the Methanolic Extract of Apamarga Kshara Against Trichomonas vaginalis Carbamate Kinase (TvCK): An Enzoinformatics Approach. Interdiscip Sci. 2015 Aug 27.
51 Zahir F, Rabbani G, Khan RH, Rizvi SJ, Jamal MS, Abuzenadah AM. The pharmacological features of bilirubin: the question of the century. Cell Mol Biol Lett. 2015 Sep;20(3):418-47. doi: 10.1515/cmble-2015-0012.
52 Dallol A, Buhmeida A, Merdad A, Al-Maghrabi J, Gari MA, Abu-Elmagd MM, Elaimi A, Assidi M, Chaudhary AG, Abuzenadah AM, Nedjadi T, Ermiah E, Alkhayyat SS, Al-Qahtani MH. Frequent methylation of the KLOTHO gene and overexpression of the FGFR4 receptor in invasive ductal carcinoma of the breast. Tumour Biol. 2015 Dec;36(12):9677-83. doi: 10.1007/s13277-015-3733-3.
53 Rasool M, Malik A, Khan KM, Qureshi MS, Shabbir B, Zahid S, Asif M, Manan A, Rashid S, Khan SR, Arsalan HM, Alam R, Arooj M, Qazi MH, Chaudhary AG, Abuzenadah AM, Al-Qahtani MH, Karim S. Assessment of biochemical and antioxidative status in patients suffering from dengue fever. J Huazhong Univ Sci Technolog Med Sci. 2015 Jun;35(3):411-8. doi: 10.1007/s11596-015-1446-x.
54 Rasool M, Malik A, Naseer MI, Manan A, Ansari S, Begum I, Qazi MH, Pushparaj P, Abuzenadah AM, Al-Qahtani MH, Kamal MA, Gan S. The role of epigenetics in personalized medicine: challenges and opportunities. BMC Med Genomics. 2015;8 Suppl 1:S5. doi: 10.1186/1755-8794-8-S1-S5.
55 Khan I, Bangash M, Baeesa S, Jamal A, Carracedo A, Abuzenadah AM et al. Epidemiological trends of histopathologically WHO classified CNS tumors in developing countries: systematic review. Asian Pac J Cancer Prev. 2015;16(1):205-16.
56 Mirza Z, Schulten HJ, Farsi HM, Al-Maghrabi JA, Gari MA, Abuzenadah AM et al. Molecular Interaction of a Kinase Inhibitor Midostaurin with Anticancer Drug Targets, S100A8 and EGFR: Transcriptional Profiling and Molecular Docking Study for Kidney Cancer Therapeutics. PLoS One. 2015;10(3):e0119765.
57 Gari M, Dakhakhni M, Gari A, Alshihri E, Al-Jahdali R, Abuzenadah AM et al. Incidence and potential causative factors associated with chronic benign neutropenia in the Kingdom of Saudi Arabia. BMC Proc. 2015; 9 (Suppl 2 Selected article from the 2nd International Genomic):S1.
58 Merdad A, Karim S, Schulten HJ, Jayapal M, Dallol A, Abuzenadah AM et al. Transcriptomics profiling study of breast cancer from Kingdom of Saudi Arabia revealed altered expression of Adiponectin and Fatty Acid Binding Protein4: Is lipid metabolism associated with breast cancer? BMC Genomics. 2015;16 Suppl 1:S11.
59 Marshall CR, Farrell SA, Cushing D, Paton T, Stockley TL, Abuzenadah AM et al. Whole-exome analysis of foetal autopsy tissue reveals a frameshift mutation in OBSL1, consistent with a diagnosis of 3-M Syndrome. BMC Genomics. 2015;16 Suppl 1:S12.
60 Merdad A, Gari MA, Hussein S, Al-Khayat S, Tashkandi H, Abuzenadah AM et al. Characterization of familial breast cancer in Saudi Arabia. BMC Genomics. 2015;16 Suppl 1:S3.
61 Agarwal A, Mulgund A, Alshahrani S, Assidi M, Abuzenadah AM, et al. Reactive oxygen species and sperm DNA damage in infertile men presenting with low level leukocytospermia. ReprodBiolEndocrinol. 2014 Dec 19;12:126.
62 Ali A, Sheikh IA, Mirza Z, Gan SH, Kamal MA, Abuzenadah AM et al. Application of Proteomic Tools in Modern Nanotechnological Approaches Towards Effective Management of Neurodegenerative Disorders. Curr Drug Metab. 2014 Dec 8.
63 Malvezzi H, Sharma R, Agarwal A, Abuzenadah AM, Abu-Elmagd M. Sperm quality after density gradient centrifugation with three commercially available media: a controlled trial. Reprod Biol Endocrinol. 2014 Dec 2;12:121.
64 Alshahrani S, Agarwal A, Assidi M, Abuzenadah AM, Durairajanayagam D, et al. Infertile men older than 40 years are at higher risk of sperm DNA damage. Reprod Biol Endocrinol. 2014 Nov 20;12:103.
65 Agarwal A, Sharma RK, Sharma R, Assidi M, Abuzenadah AM, et al. Characterizing semen parameters and their association with reactive oxygen species in infertile men. Reprod Biol Endocrinol. 2014 May 7;12:33.
66 Alam MZ, Alam Q, Jiman-Fatani A, Kamal MA, Abuzenadah AM, et al. Candida identification: a journey from conventional to molecular methods in medical mycology. World J MicrobiolBiotechnol. 2014 May;30(5):1437-51.
67 Rasool M, Malik A, Qazi AM, Sheikh IA, Manan A, Abuzenadah AM et al. Current view from Alzheimer disease to type 2 diabetes mellitus. CNS Neurol Disord Drug Targets. 2014 Apr;13(3):533-42.
68 Karim S, Mirza Z, Kamal MA, Abuzenadah AM, Azhar EI, et al. An association of virus infection with type 2 diabetes and Alzheimer's disease. CNS Neurol Disord Drug Targets. 2014 Apr;13(3):429-39.
69 Alam A, Shaikh S, Ahmad SS, Ansari MA, Shakil S, Abuzenadah AM et al. Molecular interaction of human brain acetylcholinesterase with a natural inhibitor huperzine-B: an enzoinformatics approach. CNS Neurol Disord Drug Targets. 2014 Apr;13(3):487-90.
70 Alam Q, ZubairAlam M, Karim S, Gan SH, Kamal MA, Abuzenadah AM et al. A nanotechnological approach to the management of Alzheimer disease and type 2 diabetes. CNS Neurol Disord Drug Targets. 2014 Apr;13 (3):478-86.
71 Sohrab SS, Karim S, Kamal MA, Abuzenadah AM, Chaudhary AG, et al. Bacteriophage--a common divergent therapeutic approach for Alzheimer's disease and type II diabetes mellitus. CNS Neurol Disord Drug Targets. 2014 Apr;13 (3):491-500.
72 Aliev G, Shahida K, Gan SH, Firoz C, Khan A, Abuzenadah AM et al. Alzheimer disease and type 2 diabetes mellitus: the link to tyrosine hydroxylase and probable nutritional strategies. CNS Neurol Disord Drug Targets. 2014 Apr;13(3):467-77.
73 Shaik MM, Ahmad S, Gan SH, Abuzenadah AM, Ahmad E, et al. How do periodontal infections affect the onset and progression of Alzheimer's disease?. CNS Neurol Disord Drug Targets. 2014 Apr;13(3):460-6.
74 Alam MZ, Alam Q, Kamal MA, Abuzenadah AM, Haque A. A possible link of gut microbiota alteration in type 2 diabetes and Alzheimer's disease pathogenicity: an update. CNS NeurolDisord Drug Targets. 2014 Apr;13(3):383-90.
75 Chaudhary AG, Hussein IR, Abuzenadah AM, Gari M, Bassiouni R, et al. Molecular diagnosis of fragile X syndrome using methylation sensitive techniques in a cohort of patients with intellectual disability. Pediatr Neurol. 2014 Apr;50 (4):368-76.
76 Mirza Z, Schulten HJ, Farsi HM, Al-Maghrabi JA, Gari MA, Abuzenadah AM et al. Impact of S100A8 expression on kidney cancer progression and molecular docking studies for kidney cancer therapeutics. Anticancer Res. 2014 Apr;34(4):1873-84.
77 Jabir NR, Kamal MA, Abuzenadah AM, Gan SH, Alama MN, et al. Alzheimer's and type 2 diabetes treatment via common enzyme targeting. CNS Neurol Disord Drug Targets. 2014 Mar;13(2):299-304.
78 Mirza Z, Ali A, Ashraf GM, Kamal MA, Abuzenadah AM, et al. Proteomics approaches to understand linkage between Alzheimer's disease and type 2 diabetes mellitus. CNS NeurolDisord Drug Targets. 2014 Mar;13(2):213-25.
79 Nedjadi T, Haque A, Alam Q, Gan SH, Chaudhary AG, Abuzenadah AM et al. Genomic linkage between Alzheimer's disease and type 2 diabetes. CNS Neurol Disord Drug Targets. 2014 Mar;13(2):203-12.
80 Buhmeida A, Dallol A, Merdad A, Al-Maghrabi J, Gari MA, Abuzenadah AM et al. High fibroblast growth factor 19 (FGF19) expression predicts worse prognosis in invasive ductal carcinoma of breast. Tumour Biol. 2014 Mar;35(3):2817-24.
81 Merdad A, Karim S, Schulten HJ, Dallol A, Buhmeida A, Abuzenadah AM et al. Expression of matrix metalloproteinases (MMPs) in primary human breast cancer: MMP-9 as a potential biomarker for cancer invasion and metastasis. Anticancer Res. 2014 Mar;34(3):1355-66.
82 Jamal MS, Parveen S, Beg MA, Suhail M, Chaudhary AG, Abuzenadah AM et al. Anticancer compound plumbagin and its molecular targets: a structural insight into the inhibitory mechanisms using computational approaches. PLoS One. 2014 ;9(2):e87309.
83 Harakeh S, Diab-Assaf M, Azar R, Hassan HM, Tayeb S, Abuzenadah AM et al. Epigallocatechin-3-gallate inhibits tax-dependent activation of nuclear factor kappa B and of matrix metalloproteinase 9 in human T-cell lymphotropic virus-1 positive leukemia cells. Asian Pac J Cancer Prev. 2014;15 (3):1219-25.
84 Karim S, Mirza Z, Kamal MA, Abuzenadah AM, Azhar EI, et al. The role of viruses in neurodegenerative and neurobehavioral diseases. CNS NeurolDisord Drug Targets. 2014;13 (7):1213-23.
85 Bibi F, Yasir M, Sohrab SS, Azhar EI, Al-Qahtani MH, Abuzenadah AM et al. Link between chronic bacterial inflammation and Alzheimer disease. CNS NeurolDisord Drug Targets. 2014;13 (7):1140-7.
86 Karim S, Mirza Z, Ansari SA, Rasool M, Iqbal Z, Abuzenadah AM et al. Transcriptomics study of neurodegenerative disease: emphasis on synaptic dysfunction mechanism in Alzheimer's disease. CNS NeurolDisord Drug Targets. 2014;13 (7):1202-12.
87 Karim S, Mirza Z, Kamal MA, Abuzenadah AM, Al-Qahtani MH. Gene expression analysis approach to establish possible links between Parkinson's disease, cancer and cardiovascular diseases. CNS NeurolDisord Drug Targets. 2014;13 (8):1334-45.
88 Abuzenadah AM, Zaher GF, Dallol A, Damanhouri GA, Chaudhary AG, et al. Identification of a novel SBF2 missense mutation associated with a rare case of thrombocytopenia using whole-exome sequencing. J Thromb Thrombolysis. 2013 Nov;36 (4):501-6.
89 Qashqari H, Al-Mars A, Chaudhary A, Abuzenadah AM, Damanhouri G, et al. Understanding the molecular mechanism(s) of hepatitis C virus (HCV) induced interferon resistance. Infect Genet Evol. 2013 Oct;19:113-9.
90 Paracha UZ, Fatima K, Alqahtani M, Chaudhary A, Abuzenadah AM, et al. Oxidative stress and hepatitis C virus. Virol J. 2013 Aug 7;10:251.
91 Hampshire DJ, Abuzenadah AM, Cartwright A, Al-Shammari NS, Coyle RE, et al. Identification and characterisation of mutations associated with von Willebrand disease in a Turkish patient cohort. ThrombHaemost. 2013 Aug;110 (2):264-74.
92 Tabrez S, Priyadarshini M, Urooj M, Shakil S, Ashraf GM, Abuzenadah AM et al. Cancer chemoprevention by polyphenols and their potential application as nanomedicine. J Environ Sci Health C Environ CarcinogEcotoxicol Rev. 2013;31 (1):67-98.
93 Turki R, Sait K, Anfinan N, Sohrab SS, Abuzenadah AM. Prevalence of human papillomavirus in women from Saudi Arabia. Asian Pac J Cancer Prev. 2013;14 (5):3177-81.
94 Abuzenadah AM. The use of Polycomb Gene Targets Methylation as Biomarkers for Hematological Malignancies. World Journal of Medical Services 9 Prev. 2013, no. 4:420-66
95 Kothandaraman N, Gauthaman K, Pushparaj PN, Meenakumari G. Chaudhary AG. Abuzenadah AM, Gari MA, Al-Qahtani M, Manikandan J. Identification of Unique Mirna Biomarkers in Colorectal Adenoma and Carcinoma Using Microarray: Evaluation of Their Putative Role in Disease Progression. Cell Biology Prev. 2013
96 Mirza Z, Kamal MA, Abuzenadah AM, Al-Qahtani MH, Karim S. Establishing Genomic/Transcriptomic Links between Alzheimer's Disease and Type II Diabetes Mellitus by Meta- Analysis Approach. CNS & neurological disorders drug targets Prev. 2013
97 Dallol A, Al-Maghrabi J, Buhmeida A, Gari MA, Chaudhary AG, Abuzenadah AM et al. Methylation of the polycomb group target genes is a possible biomarker for favorable prognosis in colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2012 Nov;21(11):2069-75.
98 Ali R, Mirza Z, Ashraf GM, Kamal MA, Ansari SA, Abuzenadah AM et al. New anticancer agents: recent developments in tumor therapy. Anticancer Res. 2012 Jul;32 (7):2999-3005.
99 Priyadarshini M, Kamal MA, Greig NH, Realef M, Abuzenadah AM, et al. Alzheimer's disease and type 2 diabetes: exploring the association to obesity and tyrosine hydroxylase. CNS NeurolDisord Drug Targets. 2012 Jun 1;11(4): 482-9.
100 Shakil S, Kamal MA, Tabrez S, Abuzenadah AM, Chaudhary AG, et al. Molecular interaction of the antineoplastic drug, methotrexate with human brain acetylcholinesterase: a docking study. CNS NeurolDisord Drug Targets. 2012 Mar;11(2):142-7.
101 Begum M, Karim S, Malik A, Khurshid R, Asif M, Abuzenadah AM et al. CA 15-3 (Mucin-1) and physiological characteristics of breast cancer from Lahore, Pakistan. Asian Pac J Cancer Prev. 2012;13 (10):5257-61.
102 Tabrez S, Jabir, NR, Shakil S, Greig NH, Alam Q, Abuzenadah AM, Damanhouri GA, Kamal MA. A synopsis on the role of tyrosine hydroxylase in Parkinson's disease. CNS & neurological disorders drug targets 11 395-409 Prev. 2012
103 Dallol A, Banni H, Gari M, Al-Qahtani MH, Abuzenadah AM, Chaudhary A, Bidwell JR, Kafienah W. Five novel Glucose-6-Phosphate Dehydrogenase deficiency haplotypes that correlate with disease severity. Journal of Translational Medicine 24;10 (1):199. 2012
104 Gari M, Al-Sayes FM, Ahmed F, Peerzada AA, Mira LS, Al-Qahtani M, Dallol A, Abuzenadah AM Chaudhary A, Mahnashi M, Damanhouri G. JAK2 Mutations in Chronic Myeloproliferative Neoplasm Patients in the Western Regions of Saudi Arabia. Open J Blood Diseases 2, 1-21. 2012
105 Schulten HJ, Al-Maghrabi J, Al-Ghamdi K, Salama S, Al-Muhayawi S, Abuzenadah AM et al. Mutational screening of RET, HRAS, KRAS, NRAS, BRAF, AKT1, and CTNNB1 in medullary thyroid carcinoma. Anticancer Res. 2011 Dec;31 (12):4179-83.
106 Shakil S, Azhar EI, Tabrez S, Kamal MA, Jabir NR, Abuzenadah AM et al. New Delhi metallo-β-lactamase (NDM-1): an update. J Chemother. 2011 Oct;23 (5):263-5.
107 Buhmeida A, Merdad A, Al-Maghrabi J, Al-Thobaiti F, Ata M, Abuzenadah AM et al. RASSF1A methylation is predictive of poor prognosis in female breast cancer in a background of overall low methylation frequency. Anticancer Res. 2011 Sep;31(9):2975-81.
108 Tabrez S, Shakil S, Urooj M, Damanhouri GA, Abuzenadah AM, et al. Genotoxicity testing and biomarker studies on surface waters: an overview of the techniques and their efficacies. J Environ Sci Health C Environ CarcinogEcotoxicol Rev. 2011 Jul;29(3):250-75.
109 Buhmeida A, Al-Maghrabi J, Merdad A, Al-Thubaity F, Chaudhary A, Abuzenadah AM et al. Prognostic value of mitotic counts in breast cancer of Saudi Arabian patients. Anticancer Res. 2011 Jan;31(1):97-103.
110 Abuzenadah AM, Hussein IM, Damanhouri GA, A-Sayes FM, Gari MA, et al. Molecular basis of β-thalassemia in the western province of Saudi Arabia: identification of rare β-thalassemia mutations. Hemoglobin. 2011;35(4):346-57.
111 Chaudhary AG, Al-Juhani MA, Azam J, Al- Maghrabi J, Gari M, Abuzenadah AM, Al-Qahtani M. Evaluation of Her-2/neu gene amplification in Saud female breast cancer patients using quantitative real-time PCR and fluorescence in situ hybridization. WASJ, 2011; 14(10):1445-1452
112 Al-Sayes F, Gari M, Qusti S, Bagatian N, Abuzenadah AM. Prevalence of Iron Deficiency and Iron Deficiency and Iron Deficiency Anemia among females at University Stage. Journal of Medical Laboratory and Diagnosis. 2011 Vol 2(1), 5-11
113 Al-Khattabi H, Kelany A, Buhmeida A, Al-Maghrabi J, Lari S, Abuzenadah AM et al. Evaluation of HER-2/neu gene amplification by fluorescence in situ hybridization and immunohistochemistry in saudi female breast cancer. Anticancer Res. 2010 Oct;30(10):4081-8.
114 Buhmeida A, Al-Maghrabi J, Merdad A, Al-Thubaity F, Chaudhary A, Abuzenadah AM et al. Nuclear morphometry in prognostication of breast cancer in Saudi Arabian patients: comparison with European and African breast cancer. Anticancer Res. 2010 Jun;30(6):2185-91.
115 Al-Qahtani MH, Baghlab I, Chaudhary AG, Abuzenadah AM, Bamanie A, et al. Spectrum of GJB2 mutations in a cohort of nonsyndromic hearing loss cases from the Kingdom of Saudi Arabia. Genet Test Mol Biomarkers. 2010 Feb;14(1):79-83.
116 Gari MA, Chaudhary AG, Al-Qahtani MH, Abuzenadah AM, Waseem A, et al. Frequency of Mediterranean mutation among a group of Saudi G6PD patients in Western region-Jeddah. Int J Lab Hematol. 2010 Feb;32(1 Pt 2):17-21.
117 Abuzenadah AM, Adb Elkader SM, Saiem Aldahr M. Impact of Mild Versus Moderate Intensity Aerobic Exercise Training on Leptin and Selected Innate Immune System Response in Obese Asthmatic Patients. Middle East Journal of Scientific Research 5(1) 2010; 01-05
118 Abuzenadah AM. Association of Specific Structural and Numerical Chromosomal Abnormalities in Lymphoma Cell Lines. Extent of Genetic Instability. Academic Journal of Cancer Research. 2009 2(1); 51-60
119 Gari M, Abuzenadah AM Chaudhary A, Al-Qahtani M, Banni H, et al. Detection of FLT3 oncogene mutations in acute myeloid leukemia using conformation sensitive gel electrophoresis. Int J Mol Sci. 2008 Nov;9(11):2194-204.
120 Ardawi MS, Nasrat HA, Rouzi AA, Qari MH, Al-Qahtani MH, Abuzenadah AM et al. The effect of cigarette or sheesha smoking on first-trimester markers of Down syndrome. BJOG. 2007 Nov;114(11):1397-401.
121 Ardawi MS, Nasrat HA, Rouzi AA, Qari MH, Al-Qahtani MH, Abuzenadah AM et al. Maternal serum free-beta-chorionic gonadotrophin, pregnancy-associated plasma protein-A and fetal nuchal translucency thickness at 10-13(+6) weeks in relation to co-variables in pregnant Saudi women. PrenatDiagn. 2007 Apr;27(4):303-11.
122 Allen S, Abuzenadah AM, Hinks J, Blagg JL, Gursel T, et al. A novel von Willebrand disease-causing mutation (Arg273Trp) in the von Willebrand factor propeptide that results in defective multimerization and secretion. Blood. 2000 Jul 15;96(2):560-8.
123 Allen S, Abuzenadah AM, Blagg JL, Hinks J, Nesbitt IM, et al. Two novel type 2N von Willebrand disease-causing mutations that result in defective factor VIII binding, multimerization, and secretion of von Willebrand factor. Blood. 2000 Mar 15;95(6):2000-7.
124 Williams IJ, Abuzenadah AM, Winship PR, Preston FE, Dolan G, et al. Precise carrier diagnosis in families with haemophilia A: use of conformation sensitive gel electrophoresis for mutation screening and polymorphism analysis. Thromb Haemost. 1998 Apr;79(4):723-6.
125 Cooper PC, Hampton KK, Makris M, Abuzenadah AM, Paul B, et al. Further evidence that activated protein C resistance can be misdiagnosed as inherited functional protein S deficiency. Br J Haematol. 1994 Sep;88(1):201-3.
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